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KMID : 0931320080080020065
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대한상부위장관.헬리코박터학회지
2008 Volume.8 No. 2 p.65 ~ p.70
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Diagnosis of Helicobacter pylori Infection
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Jee Sam-Ryong
Seol Sang-Young
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Abstract
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The diagnostic methods of H. pylori infection may be classified as invasive, i.e., requiring an endoscopy, and non-invasive tests. Histology and culture still play an important part in the diagnosis of H. pylori. Culture provides information about pathogen characteristics and susceptibility to antibiotics. Owing to a high prevalence of gastric cancer and low cost of endoscopy, rapid urease test and histology are widely used in Korea before eradication therapy. The urea breath test is the most reliable nonendoscopic test to document eradication of H. pylori infection. Stool antigen tests have been evaluated in pre- and post-treatment settings. The serological tests are not all equivalent and different tests are applied in different situations. The detection of H. pylori antibodies in urine and saliva has no current role in patient management. There is no single test that can be considered the gold standard for detecting H. pylori. The most appropriate test for any specific situation will be influenced by the clinical circumstances, the availability and costs of the individual diagnostic tests.
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KEYWORD
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Helicobacter pylori, Diagnosis, Invasive test, Non-invasive test, Stool antigen test
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